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Brett Mitchell, PhD, FAHA

Brett Mitchell
Brett Mitchell, PhD, FAHA

Professor

Director, Summer Undergraduate Research Program

Director, Medical Sciences MS Degree Program

Contact

Medical Physiology
8447 John Sharp Pkwy
2412 Medical Research and Education Building 2
Bryan, TX 77807
brettmitchell@tamu.edu
Phone: 979.436.0751

Biography

Brett Mitchell is a Professor of Medical Physiology located in Bryan, Texas. He received his BA in Health Fitness/Biology from Gustavus Adolphus College in 1995, and his MS in Human Physiology from the University of Wisconsin-La Crosse in 1996. He received his PhD in Physiology from the Medical College of Georgia in 2003, where he worked with Dr. Clinton Webb studying endothelial dysfunction and hypertension. His postdoctoral work was performed at Universities Space Research Association, located at NASA's Johnson Space Center in Houston. Brett then joined the faculty of Baylor College of Medicine in the Department of Molecular Physiology and Biophysics, where he began studying the role of immunophilins in endothelial function and blood pressure regulation. Brett joined the faculty at the Texas A&M University Health Science Center in July 2007 as an Assistant Professor and in 2012 received tenure and was promoted to Associate Professor. In 2020 he was promoted to Professor.

Education and Training

  • Gustavus Adolphus School, BA, Health Fitness/Biology, 1995
  • University of Wisconsin-LaCrosse, MS, Human Physiology, 1996
  • Medical School of Georgia, PhD, Physiology, 2003

Research Interests

  • Immunity, Inflammation, and Hypertension
  • Our research focuses on understanding the molecular mechanisms involved in the development of endothelial dysfunction and hypertension caused by various immune system activators such as salt, angiotensin II, viruses, and bacteria. Alterations in both the innate and adaptive immune system can elicit persistent, pro-inflammatory effects on major blood pressure-regulating organs such as the kidney and blood vessels. Our goal is to develop therapies that target certain immune cells and the immune system-cardiovascular system interaction in an effort to reduce the incidence and severity of hypertension. Our research focuses on the following:
  • Renal lymphatic vessels and immune cell trafficking in hypertension
  • Immunosuppressive drugs and how they cause hypertension
  • Hypertension and organ damage during pregnancy (Preeclampsia)

Awards, Recognition and Service

  • Distinguished Alumni Award - Graduate School conferred by Augusta University - (Augusta, Georgia, United States)
  • Established Professional/Research Career Enhancement Awards conferred by American Physiological Society - (Bethesda, Maryland, United States)
  • Cardiovascular Section Awards/Young Investigator Award conferred by American Physiological Society - (Bethesda, Maryland, United States)

Representative Publications

 

Lab Members

Valorie Chiasson, BS
Research Associate
Research Group: Dr. Brett Mitchell
vchiasson@tamu.edu

Bethany Goodlett, BS
Research Assistant
Research Group: Dr. Brett Mitchell
bethany-goodlett@tamu.edu