Kamlesh K Yadav , MTech, PhD
Associate Professor
Contact
Molecular & Cellular Medicine
1020 Holcombe Blvd
Room 1607
Houston,
TX
77030
kamlesh.yadav@tamu.edu
Phone: 713.677.7752
Biography
Dr. Yadav has been engaged in research in both the fields of Engineering and Medicine for the past 20 years both in academic and industrial settings. He has carried out seminal studies in the field of cell-signaling, especially focused on the RAS-MAPK pathway. He was one of the first in the field to develop large-molecule inhibitors to inactivate the RAS oncogene (Nature Genetics 2007, PNAS 2010, Nature Chemical Biology 2011, Nature Structural and Molecular Biology 2016, Patent WO2012122059A1).
Another aspect of his research focuses on studying various aspects of oncology (specifically prostate cancer). These include its biology, prognosis, and therapy, in order to develop new biomarkers for personalized diagnosis and treatment. With his industrial training in digital health, he has also contributed extensively in clinical data mining, and genomic data analysis. (Cell 2019, JCEU 2019, J of Urology 2019, Cancer Reports 2018, eLife 2018, J of Urology 2018, Translational Oncology 2017 and Oncotarget 2016).
Education and Training
- New York University (Cell and Molecular Biology), PhD, 2010
- IIT Kanpur (Environmental Engineering & Management), MTech, 2004
- Banaras Hindu University, Varanasi (Biochemistry, Metabolism & Molecular Biology), MSc, 2001
- Burdwan University, BSc, 1999
Professional Certifications
- 2020 Leadership course in Medical Education from Harvard Macy Institute
- 2020 Certified training in TBL through the Team Based Learning Consortium (TBLC)
- 2016 Grant writing workshop, AUA, Linthicum, MD
- 2013 EpiWorkshop-2013 (Cornell Univ) for genomic-data analysis using Unix
- 2012 Trained in PARTEK for genomic data analysis
Research Interests
- Digital health: Clinical data analysis, EHR mining, Genomic data analysis for biomarker identification
- Translational research: Patient-derived tumor lines to identify novel/combinatorial/synthetic-lethal drug sensitivity, and resistance development
Teaching Interests
- Co-Director, Foundation of Medicine II (FOM II): Cell and Molecular Biology, Genetics, Basic Pharmacology
- Co-Director, Team Based Learning (TBL) modules in Medicine
- Instructor: Introduction to Disease (ID): Cancer Biology and Therapeutics
- Instructor: Hematology Oncology (Heme Onc): Prostate cancer and AI in Oncology
Awards, Recognition and Service
- 2020 TAMU grant to attend Harvard Macy Institute’s Leadership in Medical Education course.
- 2018-19 Principal Scientist Sema4 genomics, CT
- 2014-19 Assistant Professor of Urology, Mount Sinai School of Medicine New York
- 2016 Selected for Early Career Investigators Workshop held by the AUA, Linthicum, MD
- 2014 Competitive Prostate Cancer Foundation Young Investigator Award
- 2012 Competitive DoD PCRP Postdoctoral Training Award
- 2009 Competitive Travel Fellowship by the American Society of Biochemistry and Molecular Biology (ASBMB) for the EB2009 meeting, New Orleans,
- 2009 Graduate School of Arts and Science (GSAS) NYU travel award
- 2001 Banaras Hindu University Gold medal for outstanding scholar
- 2000 NET-CSIR Junior Research Fellowship
Patents
- Hydrogen bond Surrogate macrocycles as modulators of Ras/Sos, WSGR Docket No. 3224-754.101 Inventors: Bar-Sagi, Dafna; Arora PS; Patgiri, A; Yadav, Kamlesh, K.
- Methods of modulating binding of son of sevenless to phosphatidic acid Pub. No.: WO/2008/137819, Docket No.: 29527.0683 Application No. 13/568878. Inventors: Bar-Sagi, Dafna; Chen, Zhao; Skowromek, Karl; Yadav, Kamlesh, K.