Jerome P. Trezciakowski, PhD

Education and Training

• University of Florida, PhD, Pharmacology, 1978
• Cornell University Medical College, Post-doctoral Research

Research Interests

• Biomathematics, particularly the application of nonlinear dynamics, signal processing techniques and pattern analysis to pharmacological and physiological systems. Some areas under current investigation:
• Quantifying cell surface texture
• The Atomic Force Microscope (AFM) in scanning mode allows detailed examination of cell surfaces at nanoscale resolutions and can track changes in surface texture in response to physiological and pathophysiological stimuli. Texture characterization requires quantifying the overall degree of roughness (fractal dimension) as well as the distribution or clustering of roughness (lacunarity). Lacunarity is a confounding factor in roughness assessment; it is not scale-invariant and there is no established method to interpret the changes in scale dependence that occur as fractal dimension varies.
• Predicting age-related renal damage and dysfunction
• In collaboration with Dr. Alan Parrish, we are developing a model to allow assessment of the degree of renal damage based on measurese of a small number of indices of renal function such as BUN, KIM-1, urine volume and urine albumin. Early detection of renal disease in the aging population could potentially allow intervention and slow or prevent the progression of damage.

Awards, Recognition and Service

• Member of the Academy of Distinguished Medical Educators conferred by Texas A&M University - (College Station, Texas, United States)