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Research Areas


College of Medicine Research Focus Areas and Faculty Listings

Genetics, Genomics, and Network Biology

Use of model organisms to study normal physiology and disease; use of quantitative, systems-based approaches to gain insight into the molecular/cellular/biochemical networks that underlie biological phenomena.

Faculty

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Keywords: gene regulation, developmental genetics, bioinformatics, microbial and viral genetics, cancer genetics, epigenetics, polymorphism, multi genetic inheritance, mutations

Cancer, Cell, and Developmental Biology

Regulation of developmental processes, including those that are dysregulated in cancer, such as cell cycle regulation, control of cell survival, lifespan and cell death, the role of the innate and adaptive immunity in cancer and immunotherapy, molecular and cellular mechanisms of cancer initiation and pathogenesis, tumor angiogenesis, cell invasion and metastasis, metabolic dysregulation in cancer, lymphatics in cancer progression, and the design and application of mouse models of human cancer.

Faculty

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Keywords: cell growth, invasion, metastasis, apoptosis, angiogenesis, cancer stem cells, metabolic/mitochondrial dysfunction

Infection, Immunity, and Inflammation

Research related to infection and the subsequent host response; innate and adaptive immune mechanisms of clearance; inflammatory responses; genetic evaluation of virulence determinants that affect colonization of various tissues and systems; disease pathologies unrelated to infectious diseases; or to which etiology is unclear; e.g., diabetes, neurodegenerative disease; differentiation of mesenchymal stem cells for immune function and wound healing.

Faculty

  • Firstname Lastname, MD
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  • FirstName LName, PhD
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Keywords: infection; inflammation; microbial pathogenesis; bacteriology; virology; immunology; cytokines; chemokines; phagocytes (macrophages, neutrophils, dendritic cells); complement; wound healing; mesenchymal stem cells

Brain, Behavior, Psychiatric, and Neurological Disorders

Normal neural development and neurodevelopmental disorders, behavior, adaptation to injury and disease, psychiatric disorders

Keywords: Brain and spinal trauma, cerebrovascular stroke and other neurovascular dysfunction, neuroinflammation, Autism Spectrum Disorders, Fetal Alcohol Spectrum Disorders, neuro-oncology, neuro-muscular disease, autonomic dysfunction, brain-gut and brain-endocrine function, addiction, psychosocial trauma and social determinants of brain health, post-traumatic stress disorder, anxiety disorders, depression, schizophrenia, computational neuroscience, epilepsy, seizures, neurodegenerative diseases including Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA)

Cardiovascular, Lymphatic and Metabolic Disease

Research related to diseases that primarily affect the cardiovascular, lymphatic, and metabolic systems of the body; normal and pathophysiologic investigations of cardiac function and the blood vessel circulation of organs; lymphatic vessel physiology and lymphatic control of inflammation; metabolic pathophysiology of obesity and diabetes; the role of inflammation, aging, immune responses, and other stimuli influence the function of these systems; diseases including but not limited to heart failure, coronary artery disease, hypertension, lymphedema, diabetes, inflammatory bowel disease, obesity, kidney injury, liver injury, eye conditions, and cancer;

Keywords: cardiovascular disease; angiogenesis and lymphangiogenesis; lymphatic dysfunction; diabetes; obesity; heart; vessels; kidney; liver; adipose tissue; muscle cells; endothelial cells; eyes; inflammation; immune response

Biomedical Engineering (or Biotechnology) and Regenerative Medicine

Investigating the potential of stem cells in a range of diseases

Keywords: Tissue engineering; biomaterials; nanoparticle drug delivery; stem cells; regenerative medicine