Amutha Selvamani, PhD

Education and Training

• University of Madras, MS, Molecular Biology
• Texas Women's University, PhD, Molecular Biology (Neuroscience)
• Texas A&M University, Postdoctoral Fellow

Research Interests

• My research focuses primarily on IGF-1 and microRNA's (miRNA's) role in Stroke and their potential role as therapeutics post stroke. I have used miRNA profiling studies to assist discover various expression levels of post-stroke miRNA, stratified by age and sex. Additionally, my expertise lies in, in vivo miRNA delivery, miRNA profiling studies in circulation and brain tissue, biostatistical analysis, in situ hybridizations and animal behavioral assays. In order to better understand the sexual dimorphisms that underlie stroke pathophysiology, most of my research has included both females and males to evaluate the severity of stroke, effect of miRNA treatment or mechanisms underlying neuroprotection.
• Other research interests in the recent past have also included understanding the effect of stroke on alcohol intake and ow shift work affects pathological outcomes following stroke. In my short and long-term future, I would like to focus my research towards women's health issues especially towards a) Stroke related neuronal injury and functional impairment in the aging and aged females b) Mechanistic differences underlying sexual dimorphism in miRNA treatment and c) Potential therapeutic intervention post-stroke.