Medical Science Research Areas

This group focuses on understanding how proteins are synthesized and assembled into functional macromolecules. State of the art biophysical technologies are exploited to define mechanisms for protein folding, and protein trafficking in the endoplasmic reticulum and nucleus. Reverse genetic approaches are used to elucidate the roles of newly discovered proteins and define functional protein domains. Most researchers have strong collaborative ties with Texas A&M University groups in the chemistry and biochemistry/biophysics departments.

In the post-genomic era, two major trends have revolutionized medical research in the cardiovascular and lymphatic fields. First, traditional medical disciplines of physiology, anatomy, biochemistry, pharmacology and pathology have become more integrated with other fields, including bioengineering, instrumentation, and computer technology, creating a more holistic approach to complex problems in cardiovascular biology and medicine. Second, remarkable advances in molecular and cell biology have exponentially increased the ability of medical researchers to move knowledge of gene and protein functions from the bench to the clinical bedside.

Research in this area spans a wide range of biological processes, from events that occur within the nucleus to those in the extracellular matrix. Individual research programs focus on understanding basic cellular mechanisms (i.e. DNA replication, transcription and protein sorting), molecules that control complex regulatory pathways (signal transduction, gene regulation, epigenetics, development and differentiation), and the molecular basis for cancer. Most faculty members belong to multi-disciplinary research groups affiliated with Texas A&M University, including Texas A&M interdisciplinary programs in genetics, neurosciences and virology.

The overall educational goal of this track is to prepare future biomedical researchers who can interact effectively with the spectrum of clinical providers and community members, and function efficiently within large research teams, either as members or as team leaders. The curriculum in this track is designed to provide a strong foundation in biological science along with activities that will encourage team-oriented projects, enhance communication between team members from different disciplinary backgrounds, develop leadership skills, and provide the foundation for broad understanding of pertinent scientific, medical, and regulatory issues.